Perfluorocarbon liquid as medium-term tamponade for macular hole surgery: No prone positioning

The aim of this case series is to evaluate the anatomical and functional outcomes in the surgical management of macular hole (MH) using perfluorocarbon liquid (PFCL) as a postoperative tamponade agent, followed by staged removal after 2–3 weeks. This case series includes three cases of full-thickness MH in which PFCL was used as a postoperative endotamponade followed by staged removal after 2–3 weeks. In all three cases, successful MH closure was observed both anatomically and functionally, as confirmed by ocular coherence tomography findings and postoperative best-corrected visual acuity. Inflammatory deposits were detected in two of our cases, which was noted behind the posterior capsule of the lens, in the perivascular regions of the retina, and predominantly in the inferior retina. These deposits were noted to have resolved in subsequent follow-up visits. No significant adverse effects were observed when PFCL was used as a medium-term tamponade in any of the three cases. PFCL medium-term tamponade in cases of MHs completely obviates the need for prone positioning and is helpful in cases where posturing can be a detrimental factor in the outcome of surgery such as obesity and cervical spine issues.