What question did this study set out to answer?

To assess the independent and combined effects of smoking, alcohol consumption, paan chewing, and oral hygiene on the risk of oral cavity cancer.

January 4, 2002International Journal of CancerOpen Access

Oral cancer in southern India: The influence of smoking, drinking, paan‐chewing and oral hygiene

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Authors

PBPrabha BalaramUniversiti Sains Malaysia HSHema SridharKidwai Memorial Institute of Oncology TRThangarajan RajkumarInserm

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Implication

Case-control study reveals paan chewing, smoking, alcohol use, and poor oral hygiene substantially increase oral cancer risk in adults, highlighting key targets for regional prevention.

Key Points

To assess the independent and combined effects of smoking, alcohol consumption, paan chewing, and oral hygiene on the risk of oral cavity cancer.
Conducted a multicenter case-control study between 1996 and 1999 across three centers in Southern India (Bangalore, Madras, Trivandrum) enrolling 591 incident oral cavity cancer cases and 582 age- and gender-matched hospital controls.
Calculated odds ratios (ORs) and 95% confidence intervals (CIs) using unconditional multiple logistic regression adjusted for age, gender, center, education, chewing, and (in men) smoking and drinking.
In men, smoking ≥20 bidi or equivalents per day (OR 2.5, 95% CI 1.4–4.4) and alcohol consumption (OR 2.2, 95% CI 1.4–3.3) significantly increased oral cancer risk, together accounting for 35% of male cases.
Paan chewing dramatically elevated oral cancer risk, with higher odds in women (OR 42, 95% CI 24–76) than men (OR 5.1, 95% CI 3.4–7.8), conferring elevated risk both with tobacco (OR 6.1 in men, 46 in women) and without tobacco (OR 4.2 in men, 16.4 in women).
Paan-tobacco chewing accounted for 49% of oral cancers in men, whereas paan chewing and poor oral hygiene explained 95% of oral cancers in women.

Cite This Study

Balaram et al. (2002) studied this question.

synapsesocial.com/papers/6a04ac4ab5867de794591ce6 https://doi.org/10.1002/ijc.10200

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Implication

Case-control study reveals paan chewing, smoking, alcohol use, and poor oral hygiene substantially increase oral cancer risk in adults, highlighting key targets for regional prevention.

Oral cancer in southern India: The influence of smoking, drinking, paan‐chewing and oral hygiene

Discussion

Member takes

Implication

Key Points

Cite This Study

Oral cancer in southern India: The influence of smoking, drinking, paan‐chewing and oral hygiene

Discussion

Member takes

Implication

Key Points

Cite This Study

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