Key result
Uncontrolled hypertension linked to ~115% higher cardiovascular mortality in adults aged 35 to 59.
Why the study?
Large-scale evidence on hypertension prevalence, management, and its expected impact on cardiovascular mortality in Cuba was lacking despite national prioritisation in primary care.
Does uncontrolled hypertension increase the risk of premature cardiovascular mortality in the general adult population of Cuba?
Cohort (n=136,111)
Yes
Does uncontrolled hypertension increase the risk of premature cardiovascular mortality in the general adult population of Cuba?
Effect estimate: RR 2.15 (95% CI 1.88-2.46)
In Cuba, a third of adults have hypertension, and poor blood pressure control accounts for approximately 20% of premature cardiovascular deaths, highlighting a critical need for improved management.
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Uncontrolled hypertension signals excess CV mortality risk in Cuba; extends observational data but leaves causal benefits of control open for trials.
Rojas et al. (2019) conducted a cohort in Hypertension (n=136,111). Uncontrolled hypertension vs. Without uncontrolled hypertension was evaluated on Cardiovascular mortality (RR 2.15, 95% CI 1.88-2.46). Uncontrolled hypertension was associated with increased cardiovascular mortality, with rate ratios of 2.15 (95% CI 1.88-2.46) for ages 35-59, 1.86 for ages 60-69, and 1.41 for ages 70-79.
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