Key result
High circulating ANGPTL8 levels link to elevated fasting triglycerides in patients with diabetes.
Population
84 patients hospitalized for diabetes treatment
Comparison
Groups according to ANGPTL3 and ANGPTL8 levels
Design
Cross-sectional observational study
Authors
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ANGPTL8 should not guide lipid management in diabetes; leaves open causal role and need for prospective trials.
Observational (n=84)
No
Effect estimate: β 0.186 (95% CI 0.052-0.222)
p-value: p=0.002
Harada et al. (2021) conducted an observational in Diabetes (n=84). ANGPTL8 was evaluated on Fasting plasma triglyceride levels (β 0.186, 95% CI 0.052-0.222, p=0.002). In patients with diabetes, high circulating ANGPTL8 levels were significantly and independently associated with elevated fasting triglyceride levels (β 0.186, p=0.002).
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