Why the study?
Does nesiritide added to IV furosemide worsen renal function in patients with acute decompensated heart failure?
Population
162 patients with acute decompensated heart failure evaluated in a single-institution nesiritide utilization…
Comparison
Nesiritide added to IV furosemide vs IV furosemide alone
Design
Cohort
Authors
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Supports renal safety of nesiritide addition in acute decompensated HF; leaves open prospective randomized confirmation.
Does nesiritide added to IV furosemide worsen renal function in patients with acute decompensated heart failure?
In a retrospective review of patients with acute decompensated heart failure, the addition of nesiritide to IV furosemide did not result in a clinically significant worsening of renal function compared to IV furosemide alone.
Cheng et al. (2005) studied this question.
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