Key result
PCI with a third-generation stent relieves extrinsic LMCA compression and maintains 5-year patency.
Why the study?
Extrinsic left main coronary artery compression is a rare condition often associated with pulmonary artery hypertension.
Does percutaneous coronary intervention with a third-generation stent safely and effectively relieve obstruction in a patient with extrinsic LMCA compression?
Case Report (n=1)
No
Does percutaneous coronary intervention with a third-generation stent safely and effectively relieve obstruction in a patient with extrinsic LMCA compression?
Percutaneous coronary intervention with a third-generation stent is a safe and effective long-term alternative for managing extrinsic LMCA compression due to pulmonary artery enlargement.
May support stenting feasibility in rare extrinsic LMCA compression; leaves open need for prospective data before practice change.
Extrinsic left main coronary artery (LMCA) compression is a rare condition, often associated with pulmonary artery hypertension. We present the first reported case of extrinsic LMCA compression manifesting as syncope in a 35-year-old woman. Imaging confirmed significant LMCA compression due to pulmonary artery enlargement. Percutaneous coronary intervention with a third-generation stent successfully relieved the obstruction. At five-year follow-up, the stent remained patent without restenosis or fracture. This case highlights the importance of early diagnosis using multimodal imaging and demonstrates angioplasty as a safe, effective alternative for managing LMCA compression in high-risk patients. • First reported case of extrinsic left main coronary artery (LMCA) compression presenting with syncope • Successful third-generation stent placement for left coronary extrinsic compression • Five-year follow-up showed stent patency without restenosis, fracture, or hyperplasia. • Imaging crucial for early LMCA compression detection, especially in pulmonary artery enlargement • Angioplasty offers a safe alternative for high-risk patients with LMCA compression.
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Alcocer et al. (2025) conducted a case report in Extrinsic left main coronary artery compression in pulmonary hypertension (n=1). Percutaneous coronary intervention with a third-generation stent was evaluated on Stent patency without restenosis, fracture, or hyperplasia. Percutaneous coronary intervention with a third-generation stent successfully relieved extrinsic left main coronary artery compression, with the stent remaining patent at 5-year follow-up.
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