A Comprehensive Review on Emulgels: Transdermal Drug Delivery of Miconazole

Imidazole, a drug with a broad-spectrum antifungal agent used to treat localized vaginal, skin, and nail infections, is the source of miconazole, a synthetic derivative. The study's goal was to provide a novel method for increasing topical miconazole nitrate's permeability and effectiveness. Transdermal is one of the most often used drug delivery techniques due to its many advantages, such as ease of application, self-administration, decreased drug metabolism, etc. The path nevertheless has a lot of disadvantages in spite of these advantages. The delivery of drugs into the bloodstream via Topical medication distribution includes the skin, vagina, eyes, and rectal channels. Skin problems are treated with topical treatments. Hydrophobic drug delivery is one of the primary disadvantages of gels, despite their many advantages. In order to overcome this limitation and enable gels with unique properties to benefit even a hydrophobic medicinal moiety, an emulsion-based approach is being used. The dosage form created by mixing gels and emulsions is called Emulgel. The most promising method of delivering hydrophobic medications is Emulgel. An emulsion that is gelled in conjunction with gelling chemicals is called emulgel. Compared to other semi-solid formulations, the use of gels in pharmaceuticals and cosmetics is growing. The main drawback of hydrophobic drug delivery is one of the many benefits of gels. To get around this restriction, an emulsion-based strategy is employed. Thixotropic, fat-free, flexible, non-staining, long-lasting, translucent, and aesthetically pleasing are just a few of Emulgel's advantageous qualities for dermatological use. Emulgel can therefore be employed as a more effective local drug delivery method than existing ones.