Impact of disease activity on functional impairment in patients with axial spondyloarthritis is different according to the degree of radiographic progression: a cross-sectional study

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Key Points

The study aims to determine how disease activity affects functional impairment in axial spondyloarthritis based on the level of radiographic progression.
Conducted a cross-sectional analysis of patients diagnosed with axial spondyloarthritis.
Assessed disease activity and functional impairment metrics.
Evaluated the correlation between radiographic progression and functional outcomes.
Higher disease activity was significantly linked to increased functional impairment.
The degree of radiographic progression notably altered the impact of disease activity on functional outcomes.
Patients with advanced radiographic changes exhibited greater functional limitation in relation to disease activity.

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Cross-sectional study examines how disease activity impacts impairment based on radiographic progression, suggesting varying effects.

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Cho et al. (2026) studied this question.

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