What question did this study set out to answer?

To assess the transition from non-radiographic to radiographic axial spondyloarthritis and identify risk factors for this progression.

May 8, 2026BMC RheumatologyOpen Access

Progression of non-radiographic to radiographic axial spondyloarthritis: a risk model based on a chinese cohort study

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To assess the transition from non-radiographic to radiographic axial spondyloarthritis and identify risk factors for this progression.
Enrolled 572 patients with non-radiographic axial spondyloarthritis over a median follow-up of 5 years.
Conducted Cox proportional hazard regression analyses to identify risk factors for progression.
Developed a risk scoring system based on identified predictors to categorize patients into risk groups.
40.2% of patients progressed from non-radiographic to radiographic axial spondyloarthritis by follow-up.
Risk factors included unilateral grade II sacroiliitis, high disease activity, HLA-B27 positivity, and family history of spondyloarthritis, with varying hazard ratios in clinical and imaging arms.
The predictive model achieved AUCs ranging from 0.660 to 0.839 for progression prediction at different time points.

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Implication

Randomized trial evaluates risk factors for progression to radiographic axial spondyloarthritis in a Chinese cohort, suggesting targeted management strategies.

Cite This Study

Deng et al. (2026) studied this question.

synapsesocial.com/papers/69fd7d94bfa21ec5bbf05f13 https://doi.org/10.1186/s41927-026-00652-w

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Implication

Randomized trial evaluates risk factors for progression to radiographic axial spondyloarthritis in a Chinese cohort, suggesting targeted management strategies.

Progression of non-radiographic to radiographic axial spondyloarthritis: a risk model based on a chinese cohort study

Key Points

Discussion

Implication

Cite This Study

Progression of non-radiographic to radiographic axial spondyloarthritis: a risk model based on a chinese cohort study

Key Points

Discussion

Implication

Cite This Study

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