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Demonstrates antimicrobial effects in oral pathogens, suggesting potential therapeutic applications.
biofilms by 78.37 ± 0.22 %. Molecular docking studies supported the experimental findings, revealing favourable binding (LBE = -8.5 kcal/mol) within the active sites of ERG11 (5TZ1) and GtfB (8FK4). These findings highlight Calofrasolide A as a promising pyranocoumarin scaffold with potential antimicrobial and antibiofilm relevance, particularly against oral pathogenic infections.
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Zaini et al. (2026) studied this question.
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