Troponin Test, Not Only a Number: An Unusual Case of False Positive
Key result
Scantibodies HBT tubes identify false positive troponin by removing heterophile antibodies.
- n=1
Why the study?
Heterophile antibodies can cross-react with reagents in troponin immunoassays and cause false-positive elevations.
Does the use of neutralizing tubes (Scantibodies HBT) identify false positive troponin results caused by heterophile antibodies in a patient with chest pain?
Population
One 37-year-old male drug abuser admitted to the emergency room with chest pain
Comparison
Troponin measurements across different assays before and after Scantibodies HBT tube treatment
Design
Case report
Authors
Discussion
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Member takes
Implication
May warrant heterophile testing in unexplained troponin elevations; hypothesis-generating for neutralizing tube use.
Study Design
Type
Case Report (n=1)
Multicenter
No
Structured PICO
Does the use of neutralizing tubes (Scantibodies HBT) identify false positive troponin results caused by heterophile antibodies in a patient with chest pain?
P
Population
37-year-old male drug abuser admitted to the emergency room with chest pain (n=1)
I
Intervention
Use of Scantibodies HBT tubes to remove heterophile antibodies
C
Comparator
Standard troponin assays
O
Outcome
Correct diagnosis of troponin negativity by identifying false positive resultssurrogate
Heterophile antibodies can cause false positive troponin results, which can be correctly identified and neutralized using specific tubes like Scantibodies HBT to ensure accurate diagnosis.
Cite This Study
Salvatici et al. (2024) conducted a case report in False positive troponin due to heterophile antibodies (n=1). Scantibodies HBT tubes vs. Standard troponin assays was evaluated on Identification of true troponin status. The use of Scantibodies HBT tubes to remove heterophile antibodies successfully identified a false positive troponin result in a 37-year-old male presenting with chest pain.