Key result
Agatston score consistently predicts MACE regardless of statin use while PCE performance drops among users.
Why the study?
The predictive value of pooled cohort equations for MACE is poorly established in symptomatic patients, and non-Western studies evaluating the incremental value of coronary artery calcium are lacking.
Does coronary artery calcium scoring provide incremental value over pooled cohort equations in predicting MACE among symptomatic Asian patients with stable chest pain?
Population
Consecutive patients with stable chest pain undergoing cardiac computed tomography in a mixed Asian cohort
Comparison
Pooled cohort equations vs Agatston coronary artery calcium score
Design
Observational cohort study
Authors
Loading...
May support preferring Agatston scoring over PCE for MACE prediction in statin-treated symptomatic Asians; leaves open prospective validation before practice change.
Cohort
Does coronary artery calcium scoring provide incremental value over pooled cohort equations in predicting MACE among symptomatic Asian patients with stable chest pain?
p-value: p=0.025
In a symptomatic mixed Asian cohort, the Agatston score performed consistently in predicting MACE regardless of statin use, whereas the performance of pooled cohort equations deteriorated in statin users.
Baskaran et al. (2023) conducted a cohort in stable chest pain. Coronary artery calcium (CAC) score vs. Pooled cohort equations (PCE) was evaluated on major adverse cardiovascular events (MACE) (p=0.025). In a symptomatic mixed Asian cohort, the Agatston score performed consistently in predicting MACE across statin and non-statin users, whereas PCE performance deteriorated in statin users.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: