Why the study?
Coronary artery calcium scoring enhances ASCVD risk stratification beyond traditional risk factors, but CAC burden across PCE versus PREVENT risk groups remains unclear.
Does the distribution of coronary artery calcium burden differ across risk groups defined by the PREVENT risk calculator compared to the Pooled Cohort Equation in asymptomatic patients?
Population
7610 asymptomatic patients who underwent clinically indicated CAC scoring between 2010 and 2023
Design
Retrospective cohort study
Authors
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CAC may refine risk even in PREVENT-classified borderline groups; leaves open its incremental utility versus PCE.
Does the distribution of coronary artery calcium burden differ across risk groups defined by the PREVENT risk calculator compared to the Pooled Cohort Equation in asymptomatic patients?
A significant proportion of patients classified as low or borderline-intermediate risk by both PREVENT and PCE calculators have non-zero or high CAC scores, highlighting the utility of CAC for further risk stratification.
Gershon et al. (2025) studied this question.
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