Key result
Coronary artery calcium scores above the median were associated with a 28-fold increase in the likelihood of prevalent CAD (P<0.0001), outperforming carotid IMT (2-fold increase, P=0.015).
Why the study?
Does coronary artery calcium outperform carotid intima-media thickness for the noninvasive detection of prevalent coronary artery disease?
Population
172 adults, comprising 79 CAD patients and 93 controls, identified using coronary angiography.
Comparison
Coronary artery calcium measurement using… vs Carotid artery intima-media thickness…
Design
Case-control
Authors
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CAC may aid noninvasive detection of prevalent CAD over IMT; leaves open prospective validation before clinical adoption.
Case-Control (n=172)
Does coronary artery calcium outperform carotid intima-media thickness for the noninvasive detection of prevalent coronary artery disease?
Effect estimate: OR 28
p-value: p=<0.0001
Coronary artery calcium measured by CT is a vastly superior noninvasive index for detecting prevalent coronary artery disease compared to carotid intima-media thickness.
Terry et al. (2005) conducted a case-control in Prevalent coronary artery disease (CAD) (n=172). Coronary artery calcium (CAC) measurement vs. Carotid artery intima-media thickness (IMT) was evaluated on Likelihood of prevalent CAD (OR 28, p=<0.0001). Coronary artery calcium scores above the median were associated with a 28-fold increase in the likelihood of prevalent CAD (P<0.0001), outperforming carotid IMT (2-fold increase, P=0.015).
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