Key result
Standalone totally thoracoscopic LAA exclusion achieves 100% success at three months.
Why the study?
To assess the characteristics of LAA stump and LA volume using CCT and TOE after standalone totally thoracoscopic LAA exclusion in patients with NVAF and contraindications to OAC.
Are cardiac computed tomography and transoesophageal echocardiography useful and comparable for assessing LAA stump and LA volume after standalone thoracoscopic LAA exclusion in patients with NVAF?
Observational (n=40)
Are cardiac computed tomography and transoesophageal echocardiography useful and comparable for assessing LAA stump and LA volume after standalone thoracoscopic LAA exclusion in patients with NVAF?
Cardiac computed tomography and transoesophageal echocardiography are highly correlated and useful for identifying anatomical characteristics predisposing to a residual stump after thoracoscopic LAA exclusion.
CCT and TOE correlate for post-thoracoscopic LAA assessment; leaves open randomized trials on clinical outcomes.
AIMS: To assess the characteristics of left atrial appendage (LAA) stump and left atrial (LA) volume after standalone totally thoracoscopic LAA exclusion in 40 patients with nonvalvular atrial fibrillation (NVAF) and contraindications to oral anticoagulation (OAC), using cardiac computed tomography (CCT) and transoesophageal echocardiography (TOE). METHODS: Using CCT and TOE, we evaluated correct AtriClip Pro II positioning, the presence and characteristics of the LAA stump and the postprocedural LA volume, at 3 months' follow-up. Stump depth was measured with both CCT and TOE using a new method, based on left circumflex artery (LCX) course. RESULTS: After placement of AtriClip, all 40 patients discontinued OAC, and no stroke occurred. LAA exclusion was achieved in 40/40 patients at 3 months' follow-up. LAA stump (depth <10 mm in 12/18 stump, 67%) was observed in 18 patients. The overall (LA + LAA) volume and isolated LA volume were statistically different when comparing cases with and without LAA stump (P < 0.02). LAA ostium dimensions (perimeter and area) and LAA volume correlate with stump depth (P < 0.02). There was a high correlation between CCT and TOE in stump identification and depth measurement (P < 0.02). Compared with the baseline, CCT LA volume increased (P < 0.01) at 3 months' follow-up. CONCLUSION: Preprocedural and postprocedural CCT and TOE are useful and comparable in patients undergoing standalone totally thoracoscopic exclusion of LAA, because these imaging methods can identify anatomical LAA and LA characteristics predisposing for a postprocedural residual stump.
No takes yet. Share an insight, caveat, or question.
Mochen et al. (2023) conducted an observational in Nonvalvular atrial fibrillation with contraindications to oral anticoagulation (n=40). Standalone totally thoracoscopic LAA exclusion (AtriClip Pro II) evaluated by CCT and TOE was evaluated on LAA exclusion at 3 months. Standalone totally thoracoscopic LAA exclusion achieved 100% exclusion at 3 months, with CCT and TOE showing high correlation in identifying residual stumps (P<0.02).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: