Key result
Unsuccessful elimination of non-PV triggers during persistent AF ablation predicts ~80% higher ATa recurrence.
Why the study?
The role of nonpulmonary vein trigger ablation in persistent atrial fibrillation remained under debate.
Does successful elimination of non-pulmonary vein triggers improve freedom from atrial tachyarrhythmia recurrence in patients undergoing initial ablation for persistent atrial fibrillation?
Cohort (n=300)
Does successful elimination of non-pulmonary vein triggers improve freedom from atrial tachyarrhythmia recurrence in patients undergoing initial ablation for persistent atrial fibrillation?
Effect estimate: HR 1.80 (95% CI 1.07-2.95)
Absolute Event Rate: 38.6% vs 68.3%
p-value: p=.026
Successful elimination of non-pulmonary vein triggers during initial ablation for persistent atrial fibrillation significantly improves long-term freedom from atrial tachyarrhythmia recurrence.
No takes yet. Share an insight, caveat, or question.
Supports non-PV trigger role in persistent AF ablation outcomes; leaves open benefit of elimination in randomized trials.
Tohoku et al. (2020) conducted a cohort in persistent atrial fibrillation (PEAF) (n=300). Non-PV trigger-targeted ablation vs. Successful elimination vs unsuccessful elimination vs no non-PV triggers was evaluated on freedom from any atrial tachyarrhythmia (ATa) recurrence (HR 1.80, 95% CI 1.07-2.95, p=.026). Unsuccessful elimination of non-pulmonary vein triggers during persistent AF ablation independently predicted atrial tachyarrhythmia recurrence (HR 1.80; 95% CI 1.07-2.95; p=0.026).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: