Key result
Intravenous tissue plasminogen activator (100 mg) successfully dissolved a large, highly mobile left atrial thrombus in a patient with heart failure and atrial fibrillation.
Why the study?
Does intravenous tPA dissolve acute left atrial thrombus in a patient with heart failure and atrial fibrillation?
Population
1 patient with heart failure, atrial fibrillation, and an acute, large, pedunculated, highly mobile left…
Design
Case_report
Follow-up
2 weeks
Authors
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May offer option for refractory LA thrombus in HF/AF; hypothesis-generating and should not yet change practice.
Case Report (n=1)
No
Does intravenous tPA dissolve acute left atrial thrombus in a patient with heart failure and atrial fibrillation?
Thrombolytic therapy with tPA successfully dissolved an acute, large, mobile left atrial thrombus in a patient with heart failure and atrial fibrillation, though strict post-thrombolysis anticoagulation is crucial to prevent rebound thromboembolism.
Lee et al. (2007) conducted a case report in Acute left atrial thrombus with heart failure and atrial fibrillation (n=1). Tissue plasminogen activator (tPA) was evaluated on Thrombus resolution. Intravenous tissue plasminogen activator (100 mg) successfully dissolved a large, highly mobile left atrial thrombus in a patient with heart failure and atrial fibrillation.
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