Does dynamic global longitudinal strain after isometric hand-grip exercise predict functionally significant coronary lesions compared to FFR in patients with chronic coronary syndrome?
Dynamic GLS during isometric hand-grip exercise demonstrates high diagnostic accuracy for identifying functionally significant coronary lesions.
Aims: There is still a wide debate regarding the management of patients with chronic coronary syndrome, the choice of optimal non-invasive stress test, and the decision for coronary revascularization. Evidence has accumulated demonstrating the utility of global longitudinal strain (GLS) as a predictor of significant coronary disease. To evaluate the application of speckle tracking during resting echocardiography and after isometric loading with the hand-grip test, and to compare GLS parameters with fractional flow reserve (FFR). Methods and results: < 0.001. ΔGLS of 0.35 showed good diagnostic performance capacity (AUC 0.896, 95% CI: 0.83-0.96, specificity 85%, sensitivity 92%) for a functionally significant coronary lesion. Conclusion: Dynamic GLS during isometric hand-grip exercise is a feasible method for functional assessment in patients with chronic coronary syndrome.
Mileva et al. (Thu,) studied this question.