Key result
Arterial stiffness serves as a prognostic marker of cardiovascular damage in chronic kidney disease, providing risk information independent of traditional risk factors to help guide therapy.
Arterial stiffness serves as an important independent prognostic marker of cardiovascular damage in patients with chronic kidney disease.
Supports arterial stiffness assessment for refined CKD risk stratification; leaves open whether targeting it improves outcomes in trials.
Increased arterial stiffness is a marker of vasculopathy in chronic kidney disease (CKD) patients, suggesting a significant cardiovascular damage. Detection of arterial stiffness provides physicians with useful prognostic information independent of traditional cardiovascular (CV) risk factors. In addition, this knowledge may help guide appropriate therapeutic choices and monitor the effectiveness of antihypertensive therapies. We review the relationship between arterial stiffness and CKD, as well as the prognostic implications of increased arterial stiffness and the potential therapeutic strategies to ameliorate arterial compliance and outcome in CKD.
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Bellasi et al. (2011) conducted a review in Chronic Kidney Disease. Arterial stiffness assessment was evaluated. Arterial stiffness serves as a prognostic marker of cardiovascular damage in chronic kidney disease, providing risk information independent of traditional risk factors to help guide therapy.
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