Arterial Stiffness, Kidney Function, and Chronic Kidney Disease Progression
Key result
This review examines longitudinal studies evaluating arterial stiffness and central pressure profiles as predictors of kidney function decline and chronic kidney disease progression.
Why the study?
Does arterial stiffness predict the progressive loss of kidney function in patients with established chronic kidney disease?
Population
Patients with established chronic kidney disease (CKD)
Design
Review
Authors
Discussion
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Member takes
Implication
May support risk stratification research in CKD; leaves open prospective validation before clinical adoption.
Structured PICO
Does arterial stiffness predict the progressive loss of kidney function in patients with established chronic kidney disease?
P
Population
Patients with established chronic kidney disease (CKD)
E
Exposure
Measurement of arterial stiffness (e.g., pulse wave velocity) and central pressure profiles
O
Outcome
Chronic kidney disease progression (decline in kidney function over time)
This review highlights the potential utility of noninvasive arterial stiffness and pulse waveform measurements in predicting the progression of chronic kidney disease.
Cite This Study
Townsend et al. (2013) conducted a review in Chronic Kidney Disease (CKD). Arterial stiffness and central pressure profiles was evaluated on Declines in kidney function over time (CKD progression). This review examines longitudinal studies evaluating arterial stiffness and central pressure profiles as predictors of kidney function decline and chronic kidney disease progression.