Key result
Higher BP variability is linked to recurrent stroke, CV events, and death in stroke survivors.
Why the study?
Is increased blood pressure variability associated with recurrent ischemic stroke, cardiovascular events, and all-cause death in patients with prior stroke?
Observational
Is increased blood pressure variability associated with recurrent ischemic stroke, cardiovascular events, and all-cause death in patients with prior stroke?
p-value: p=<0.001
Increased systolic and diastolic blood pressure variability is a significant risk factor for recurrent ischemic stroke, cardiovascular events, and all-cause death in patients with prior stroke.
Does not support changing BP management in stroke survivors; hypothesis-generating for trials targeting variability.
<0.001). Conclusions- Our study adds to the growing body of literature suggesting that BPV is an important and potentially modifiable risk factor for ischemic stroke, cardiovascular events, and all-cause death. Specifically, it is the first study to demonstrate that increased BPV is associated with recurrent ischemic stroke and that diastolic BPV can be as important as systolic BPV. Future work should focus on evaluating whether actively reducing BPV, using widely available and inexpensive antihypertensive medications, reduces the risk of cardiovascular disease.
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Havenon et al. (2019) conducted an observational in Prior Stroke. Blood pressure variability was evaluated on Recurrent ischemic stroke, cardiovascular events, and all-cause death (p=<0.001). Increased blood pressure variability is associated with recurrent ischemic stroke, cardiovascular events, and all-cause death in patients with prior stroke (P<0.001).
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