Key result
Advancements in reperfusion therapy aiming at earlier and complete reperfusion significantly improved left ventricular ejection fraction from 55% to 61% in hospital survivors of acute myocardial infarction.
Why the study?
Does early and complete reperfusion therapy improve left ventricular remodeling in hospital survivors of acute myocardial infarction?
Population
813 patients with acute myocardial infarction who received reperfusion therapy and survived to hospital…
Comparison
Reperfusion therapy in later chronological… vs Reperfusion therapy in earlier chronological…
Design
Cohort
Follow-up
6 months
Authors
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Reperfusion advances linked to better LVEF post-AMI; extends observational data but leaves causality and practice change open.
Cohort (n=813)
No
Does early and complete reperfusion therapy improve left ventricular remodeling in hospital survivors of acute myocardial infarction?
Absolute Event Rate: 61% vs 55%
p-value: p=<0.001
Early and complete reperfusion therapy in AMI patients is associated with improved left ventricular ejection fraction and reduced adverse remodeling at 6 months.
Tani et al. (2007) conducted a cohort in Acute myocardial infarction (n=813). Early and complete reperfusion strategy (1999-2002) vs. Earlier reperfusion strategies (1989-1992) was evaluated on Left ventricular ejection fraction (LVEF) at 6 months (p=<0.001). Advancements in reperfusion therapy aiming at earlier and complete reperfusion significantly improved left ventricular ejection fraction from 55% to 61% in hospital survivors of acute myocardial infarction.
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