Prospective study demonstrates the feasibility of 3D-MRF for assessing cartilage health in the hip joint, suggesting effective imaging methods for osteoarthritis evaluation.
BACKGROUND: Three-dimensional MR fingerprinting (3D-MRF) has been increasingly used to assess cartilage degeneration, particularly in the knee joint, by looking into multiple relaxation parameters. A comparable 3D-MRF approach can be adapted to assess cartilage degeneration for the hip joint, with changes to accommodate specific challenges of hip joint imaging. PURPOSE: in clinically feasible scan times. STUDY TYPE: Prospective. SUBJECTS: Eight healthy subjects, three patients with mild osteoarthritis (OA), and one of the OA patients had femoral acetabular impingement (FAI). A National Institute of Standards and Technology/International Society for Magnetic Resonance in Medicine (NIST/ISMRM) system phantom was also used. FIELD STRENGTH/SEQUENCE: mapping. ASSESSMENT: maps of 3D-MRF sequence were evaluated on a NIST/ISMRM phantom and human subjects. Differences in the parametric maps between OA and healthy subjects were assessed. STATISTICAL TESTS: Regression, Bland-Altman, Kruskal-Wallis, and Wilcoxon tests were used to assess for accuracy, repeatability, and subregional variation. The P-value <0.05 indicated statistically significant. RESULTS: ) in femoral lateral compartment of the hip joint compared to healthy controls. DATA CONCLUSION: 3D-MRF may be a feasible approach for simultaneous, quantitative mapping of bilateral hip joint cartilage in healthy and mild OA patients. EVIDENCE LEVEL: 1 TECHNICAL EFFICACY: Stage 1.
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Monga et al. (2024) studied this question.
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