Key result
T2DM linked to ~13 mg/dL higher total cholesterol and elevated triglycerides in CHD patients.
Why the study?
T2DM is strongly associated with an increased prevalence of CVD and contributes to 80% of fatal outcomes in this population.
Does type 2 diabetes mellitus worsen lipid profiles and metabolic function in patients with coronary heart disease?
Cross-Sectional (n=100)
No
Does type 2 diabetes mellitus worsen lipid profiles and metabolic function in patients with coronary heart disease?
Absolute Event Rate: 213.4% vs 200.21%
Type 2 diabetes mellitus significantly exacerbates dyslipidemia in patients with coronary heart disease, highlighting the need for aggressive metabolic management.
May warrant enhanced lipid monitoring in diabetic CHD; leaves open whether intervention improves outcomes.
Introduction: T2DM is strongly associated with an increased prevalence of cardiovascular disease (CVD). It has been established that CVD is the main cause of mortality among patients with type 2 diabetes mellitus (T2DM) contributing to 80% of fatal outcomes. The consistent relationship between T2DM and CVD is well-established in observational studies, meta-analyses, and has an easily discernible biological mechanism. Aim and Objectives: This was a cross-sectional study consisting of 100 subjects of diabetic and non-diabetic with CHD attending medicine outpatient department (OPD). Result and Conclusion: The study highlights that diabetes significantly exacerbates the metabolic and cardiovascular risks in coronary heart disease (CHD) patients, affecting lipid profiles, glycemic control, and long-term survival. Effective management of these parameters is crucial to improving outcomes in diabetic CHD patients. Postoperative morbidity and early mortality were not substantially affected by diabetes; however, long-term survival in diabetic CHD patients was markedly diminished, highlighting the enduring effects of diabetes on cardiovascular health.
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Singh et al. (2025) conducted a cross-sectional in Coronary Heart Disease (n=100). Type 2 Diabetes Mellitus vs. Non-diabetic was evaluated on Total cholesterol (mg/dL). Type 2 diabetes mellitus in patients with coronary heart disease is associated with elevated total cholesterol (213.40 vs 200.21 mg/dL) and triglycerides compared to non-diabetic CHD patients.
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