Skeletal muscle mass and inflammation-based prognostic score as prognostic factors in oral cancer

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Key Points

To evaluate skeletal muscle mass and inflammation-based prognostic score as predictors of overall survival in oral cancer.
Identified optimal cut-off values for inflammation biomarkers including NLR, PLR, LMR, and PNI.
Conducted multivariate analysis to assess independent predictors of overall survival.
Analyzed the association between low skeletal muscle mass and inflammation scores with overall survival outcomes.
Low skeletal muscle mass is significantly associated with lower overall survival (P < 0.001).
High NLR and PLR are independent predictors of poor overall survival (P = 0.022 for NLR and P = 0.017 for PLR).
Increased inflammation and low PNI correlate with significantly poorer overall survival outcomes (P < 0.001).

Determines skeletal muscle mass and inflammation scores predict outcomes in oral cancer patients, suggesting clinical significance.

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Yamasaki et al. (2026) studied this question.

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