Creating an improved workflow for paper-based malaria diagnostics by integrating total lysis of whole blood

Key Points

• This research aims to enhance the detection of malaria through a new paper-based diagnostic method that ensures complete blood lysis.
• Developed a three-dimensional lysis device using laser cutting and wax printing techniques.
• Achieved 100% cellular lysis independent of blood sample composition.
• Secured viability of samples for storage up to one week at room temperature.
• Successfully integrated a device that allows for total lysis of whole blood samples.
• Facilitated the detection of malaria biomarkers effectively within the new workflow.
• Maintained sample integrity for one week at room temperature.