Factors associated with recurrent myocardial infarction after successful percutaneous coronary intervention

Background Cardiovascular diseases are the leading cause of death throughout the world and in Egypt in particular. Currently, percutaneous coronary intervention (PCI) is becoming the standard technique used to treat myocardial infarction (MI) that results from a coronary artery stenosis or/and occlusion, but some evidences show that as many as 20% of patients can develop recurrent MI after a specific period of time despite successful PCI. Aim The study assessed factors associated with recurrent MI after successful PCI. Patients and methods Quantitative retrospective study design was used. The primary data were collected from a sample size of 384 patient’s records who have been diagnosed with new recurrent MI with ST-elevation MI and with non-ST-elevation MI that occurred more than 28 days after the previous one and have been undergone PCI more than one time at Aswan Heart Centre in Egypt from January 1, 2022 to August 31, 2025. Data were analyzed using the Statistical Package for the Social Sciences, version 21. Results The study revealed that the significantly associated factors included older age [odds ratio (OR): 23.774; P <0.001]; employment (OR: 4.750; P =0.035). Then, hypertension (OR: 0.011; P <0.001) and diabetes mellitus (OR: 0.010; P <0.001) showed strong significance, and had markedly lower odds of association, though they were still contributing to recurrent MI. Conclusion The findings showed that the following factors, including older age, employment status, to different factors, including increased sedentary lifestyle, occupational stress, and greater exposure to environmental hazards, employed people were more health conscious and therefore more likely to be screened or diagnosed, leading to higher detected prevalence. Then hypertension and diabetes mellitus were found to be significantly associated with lower odds of recurrent MI after successful PCI. Recommendations Patients should maintain control of blood pressure, diabetes mellitus, a healthy lifestyle, medication adherence, and adherence to scheduled follow-up visits after PCI. Staff should do documentation properly, and researchers should conduct similar studies all over Egypt to find extended results that can be considered in developing preventive strategies countrywide. Nurses have to conduct continuous patient assessment, regular patient monitoring, and health education.