PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
May 15, 2026Current Medicinal Chemistry

Zeolite-iron Oxide Hybrid on an Interdigitated Microelectrode to Auxiliary Monitoring Abdominal Aortic Aneurysms by Aptamerantibody Sandwich

View Full Paper
Ask AI
Bookmark
Share

Authors

HWHaohua WangRDRuining DaiHXHai Xia

Discussion

Loading...

Member takes

Overview

Randomized trial demonstrates enhanced detection of osteopontin in aortic aneurysms, indicating potential for better diagnosis.

Key Points

  • This research aims to develop a sensitive sensor for detecting osteopontin to monitor abdominal aortic aneurysms.
  • Developed a zeolite-Fe-based interdigitated microelectrode sensor
  • Designed an aptamer-antibody sandwich pattern for osteopontin quantification
  • Tested sensor performance against osteopontin-spiked serum and control proteins
  • Detected osteopontin as low as 100 pM with a linear regression model (R2 = 0.9909)
  • Showed selective detection in serum without interferences from control proteins
  • Proved specific detection of osteopontin using complementary aptamer sequences

Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/6a06b940e7dec685947abd13https://doi.org/10.2174/0109298673364927251118025449
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Analyzing duplex formation with abdominal aortic aneurysm biomarker on palladium nanocube attached interdigitated electrodes2026
  2. 2Cardiac troponin I biosensing on dipole-electrodes mediated interdigitated-zeolite transducer2026
  3. 3Gold-antibody-aptamer complexed electrochemical sensing surface for septic arthritis biomarker determination2024 · 2 citations
  4. 4Harnessing in Silico Design for Electrochemical Aptasensor Optimization: Detection of Okadaic Acid (OA)2025
  5. 5Au/FeNiPO<sub>4</sub>‐Based Multiple Spectra Optoacoustic Tomography/CT Dual‐Mode Nanoprobe for Systemic Screening of Atherosclerotic Vulnerable Plaque2024 · 2 citations