Key result
Female sex, diabetes, and obesity linked to increased complication risk during AF ablation in HCM.
Why the study?
What are the predictors of procedural complications following catheter ablation for atrial fibrillation in patients with hypertrophic cardiomyopathy?
Observational
What are the predictors of procedural complications following catheter ablation for atrial fibrillation in patients with hypertrophic cardiomyopathy?
Effect estimate: OR 4.81 (95% CI 2.72-8.51)
p-value: p=<0.01
Catheter ablation for atrial fibrillation in patients with hypertrophic cardiomyopathy carries significant periprocedural risks, particularly in females, diabetics, and obese patients, necessitating careful patient selection.
May warrant caution selecting female, diabetic, or obese HCM patients for AF ablation; leaves open need for prospective validation.
<0.01). Independent predictors of complications included female sex (odds ratio [OR], 4.81; 95% CI, 2.72-8.51), diabetes mellitus (OR, 6.57; 95% CI, 2.68-16.09) and obesity (OR, 3.82; 95% CI, 1.61-9.06). Conclusions Despite some decline in procedural complications over the years, catheter ablation for AF is still associated with a relatively high periprocedural morbidity and even mortality in patients with HCM. This emphasizes the importance of careful clinical consideration, by an experienced electrophysiologist, in referring patients with HCM for an AF ablation.
No takes yet. Share an insight, caveat, or question.
Rozen et al. (2020) conducted an observational in Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy. Catheter ablation was evaluated on Procedural complications (OR 4.81, 95% CI 2.72-8.51, p=<0.01). Female sex (OR 4.81; 95% CI 2.72-8.51), diabetes (OR 6.57), and obesity (OR 3.82) independently predicted complications of catheter ablation for atrial fibrillation in hypertrophic cardiomyopathy.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: