What is the clinical evidence from this study?

Study design: Observational. Population: Suspected acute myocardial infarction (n=69). Intervention: Intravenous insulin therapy. Primary outcome: Admission plasma glucose > 7.8 mmol/L.

What question did this study set out to answer?

This study aims to clarify the prevalence of hyperglycaemia in patients receiving thrombolysis and evaluate their management.

September 1, 2003The British Journal of Diabetes

Prevalence and management of hyperglycaemia in patients given thrombolysis for acute coronary syndromes

View Full Paper

Ask AI

Bookmark

Key result

Admission hyperglycemia (>7.8 mmol/L) occurred in 46% of patients receiving thrombolysis for suspected acute myocardial infarction, but insulin was given to only 43% of those without known diabetes.

Population

69 consecutive patients who received thrombolysis on admission to a coronary care unit for suspected acute…

Design

Cohort

Authors

KBKevin BaynesEaling Hospital CMColin McintoshUniversity of Huddersfield MFMichael FeherUniversity of Oxford

Discussion

Member takes

Implication

Hyperglycemia may be undertreated in non-diabetic thrombolysis patients; leaves open whether protocols improve outcomes.

Key Points

This study aims to clarify the prevalence of hyperglycaemia in patients receiving thrombolysis and evaluate their management.
Retrospective case-note review of 69 patients treated with thrombolysis in a coronary care unit over 15 months.
Hyperglycaemia defined by admission plasma glucose > 7.8 mmol/L and random glucose > 11.0 mmol/L.
Management assessed based on insulin administration among hyperglycaemic patients, particularly those with and without diabetes.
46% of patients had plasma glucose > 7.8 mmol/L; 22% had random glucose > 11.0 mmol/L.
43% of non-diabetic patients with hyperglycaemia received intravenous insulin, while 88% of known diabetic patients were treated with insulin.
Highlighting gaps, often hyperglycaemia was not managed with insulin therapy despite incidence in coronary care settings.

Study Design

Type

Observational (n=69)

Multicenter

Structured PICO

Population

69 consecutive patients who received thrombolysis on admission to a coronary care unit for suspected acute myocardial infarction over a 15-month period

Outcome

Prevalence of hyperglycaemia and management with insulin therapy

Hyperglycemia is common in patients receiving thrombolysis for acute myocardial infarction but is inconsistently managed with insulin, highlighting the need for clear management protocols.

Cite This Study

Baynes et al. (2003) conducted an observational in Suspected acute myocardial infarction (n=69). Intravenous insulin therapy was evaluated on Admission plasma glucose > 7.8 mmol/L. Admission hyperglycemia (>7.8 mmol/L) occurred in 46% of patients receiving thrombolysis for suspected acute myocardial infarction, but insulin was given to only 43% of those without known diabetes.

synapsesocial.com/papers/6a0727f802b4a6d6a3d3e5bc https://doi.org/10.1177/14746514030030050601

View Full Paper

Ask AI

Bookmark

Prevalence and management of hyperglycaemia in patients given thrombolysis for acute coronary syndromes

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Prevalence and management of hyperglycaemia in patients given thrombolysis for acute coronary syndromes

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

Also Consider