Key result
Magnetocardiography successfully enabled the prenatal diagnosis of fetal Wolff-Parkinson-White syndrome by detecting a short PR interval and a long QRS complex with a delta wave at 35 weeks' gestation.
Why the study?
Can magnetocardiography accurately diagnose fetal Wolff-Parkinson-White syndrome prenatally?
Case Report (n=1)
Can magnetocardiography accurately diagnose fetal Wolff-Parkinson-White syndrome prenatally?
Magnetocardiography is a viable and effective tool for the prenatal diagnosis of fetal Wolff-Parkinson-White syndrome.
Answers are grounded in this paper and cite their sources.
Supports prenatal magnetocardiography for fetal WPW detection; leaves open need for prospective validation before wider use.
We report a case of fetal Wolff-Parkinson-White (WPW) syndrome diagnosed prenatally by magnetocardiography (MCG). At 32 weeks' gestation, the fetus was diagnosed to have a paroxysmal supraventricular tachycardia by ultrasonography and direct fetal electrocardiogram (ECG). Transplacental fetal therapy by maternal oral administration of propranolol resolved the fetal tachyarrhythmia. Although the wave forms of the fetal MCG at 32 weeks' gestation were normal, the fetal MCG at 35 weeks' gestation showed a short PR interval and a long QRS complex duration with a delta wave, indicating WPW syndrome. The findings of the fetal MCG were confirmed by the postnatal ECG. MCG made the prenatal diagnosis of WPW syndrome possible.
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Hosono et al. (2001) conducted a case report in Fetal Wolff-Parkinson-White (WPW) syndrome (n=1). Magnetocardiography (MCG) was evaluated on Prenatal diagnosis of WPW syndrome. Magnetocardiography successfully enabled the prenatal diagnosis of fetal Wolff-Parkinson-White syndrome by detecting a short PR interval and a long QRS complex with a delta wave at 35 weeks' gestation.
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