Key result
Fetal magnetocardiography successfully guided transplacental sotalol administration, converting supraventricular tachycardia to sinus rhythm in 1 fetus at 33 weeks gestation.
Why the study?
Does transplacental sotalol guided by fetal magnetocardiography convert supraventricular tachycardia to sinus rhythm in a fetus?
Case Report (n=1)
Does transplacental sotalol guided by fetal magnetocardiography convert supraventricular tachycardia to sinus rhythm in a fetus?
Fetal magnetocardiography is potentially useful for prenatal differentiation of supraventricular tachycardia type and guiding transplacental antiarrhythmic treatment.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for magnetocardiography-guided fetal SVT therapy; larger studies needed before clinical adoption.
We report a fetus at 33 weeks of gestation with supraventricular tachycardia, which was successfully managed by transplacental administration of an antiarrhythmic agent. Fetal magnetocardiography (fMCG) revealed supraventricular tachycardia of the long RP' tachycardia type. Transplacental administration of sotalol, instead of digoxin, was selected as the first-line drug, and it successfully converted supraventricular tachycardia to sinus rhythm. The diagnosis of the type of supraventricular tachycardia was confirmed by electrocardiography after birth. Sotalol was also effective after birth to maintain sinus rhythm. This case demonstrates that fMCG is potentially useful for prenatal differentiation of the type of supraventricular tachycardia and for prenatal treatment of fetal tachyarrhythmias.
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Abe et al. (2005) conducted a case report in Fetal supraventricular tachycardia (n=1). Fetal magnetocardiography (fMCG) and transplacental sotalol was evaluated on Conversion to sinus rhythm. Fetal magnetocardiography successfully guided transplacental sotalol administration, converting supraventricular tachycardia to sinus rhythm in 1 fetus at 33 weeks gestation.
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