Why the study?
Does intravenous procainamide administered to the mother cardiovert fetal supraventricular tachycardia refractory to digoxin and propranolol?
Does intravenous procainamide administered to the mother cardiovert fetal supraventricular tachycardia refractory to digoxin and propranolol?
Intravenous procainamide administered to the mother may be an effective strategy for temporary cardioversion of fetal supraventricular tachycardia complicated by heart failure when digoxin and propranolol fail.
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Maternal IV procainamide may temporarily cardiovert refractory fetal SVT; leaves open need for prospective trials before wider use.
Since Hyman's first phonocardiographic verification of fetal arrhythmia in 1930,1 there have been reports of persistent fetal tachycardia resulting in the delivery of infants with benign neonatal courses or severe congestive heart failure, or even in fetal loss.2 3 4 5 6 Intrauterine pharmacologic cardioversion with digoxin and propranolol has been reported previously.7 In this report we describe a case of fetal supraventricular tachycardia complicated by intrauterine congestive heart failure that was diagnosed by two-dimensional and M-mode echocardiography. The arrhythmia was temporarily cardioverted on several occasions by administering intravenous procainamide to the mother after digoxin and propranolol had failed to alter the fetal heart . . .
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Dumesic et al. (1982) studied this question.
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