Key result
Extracellular vesicles drive vascular dysfunction and thrombosis, emerging as potential biomarkers or therapeutics.
Why the study?
Atherosclerotic cardiovascular disease remains the leading cause of morbidity and mortality worldwide, with emerging evidence highlighting extracellular vesicles as key mediators of intercellular communication in immunoinflammation and atherothrombosis.
Extracellular vesicles play a dual role in atherothrombosis, driving both disease progression and vascular repair, highlighting their potential as biomarkers and therapeutic targets.
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May inform EV biomarker development in atherothrombosis; leaves open therapeutic translation pending prospective trials.
Suades et al. (2022) conducted a review in Atherothrombosis. Extracellular vesicles was evaluated. Extracellular vesicles act as key signaling molecules that drive immunoinflammation, vascular dysfunction, and thrombus formation, with potential clinical applications as biomarkers or therapeutics.
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