Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
November 10, 1983New England Journal of Medicine

Effects of Coronary-Artery Bypass Grafting on Survival

View Full Paper
Ask AI
Bookmark
Share

Key result

Coronary-artery bypass grafting reduced the incidence and severity of angina but showed no difference in survival compared to medical treatment in patients with chronic stable angina.

Why the study?

Does coronary-artery bypass grafting improve survival in patients with chronic stable angina compared to medical treatment?

Population

Almost 600 patients with chronic stable angina

Comparison

Coronary-artery bypass grafting (CABG) vs Medical treatment

Design

Editorial

Authors

EBEugene Braunwald

Discussion

Loading...

Member takes

Overview

Cautions against CABG for survival benefit in chronic stable angina without left main disease; leaves open efficacy versus contemporary medical therapy.

Key Points

  • This research aims to evaluate the effect of coronary-artery bypass grafting on patient survival among those with chronic stable angina.
  • Conducted a randomized trial comparing medically and surgically treated groups of patients with chronic stable angina.
  • Included nearly 600 patients who were assessed for differences in survival rates.
  • Focused on those without obstructive disease of the left main coronary artery.
  • Found no significant difference in survival rates between the medically treated group and the surgically treated group.
  • Confirmed that CABG reduces the incidence and severity of angina but does not extend survival.
  • Raised concerns about the increasing frequency of CABG procedures despite the lack of survival benefits.

Structured PICO

Does coronary-artery bypass grafting improve survival in patients with chronic stable angina compared to medical treatment?

P
Population
Almost 600 patients with chronic stable angina (excluding those with obstructive disease of the left main coronary artery)
I
Intervention
Coronary-artery bypass grafting (CABG)
C
Comparator
Medical treatment
O
Outcome
Survivalhard clinical

This editorial highlights that while CABG reduces angina symptoms, it does not improve survival in patients with chronic stable angina without left main disease.

Cite This Study

Eugene Braunwald (1983) conducted an editorial in Chronic stable angina (n=600). Coronary-artery bypass grafting (CABG) vs. Medical treatment was evaluated on Survival. Coronary-artery bypass grafting reduced the incidence and severity of angina but showed no difference in survival compared to medical treatment in patients with chronic stable angina.

synapsesocial.com/papers/6a076a182edded7c7b8437behttps://doi.org/10.1056/nejm198311103091911
View Full Paper
Ask AI
Bookmark
Share