Key result
Catheter ablation in octogenarians shows a 93% AF-free rate without postoperative HF hospitalizations.
Why the study?
Although catheter ablation efficacy and safety have been reported in older patients, they might diminish with age.
Does catheter ablation safely prevent atrial fibrillation recurrence and improve clinical outcomes in patients aged ≥80 years?
Observational (n=100)
No
Does catheter ablation safely prevent atrial fibrillation recurrence and improve clinical outcomes in patients aged ≥80 years?
Catheter ablation for atrial fibrillation in patients aged ≥80 years is highly effective and relatively safe, though caution is needed in those with enlarged left atrial diameters due to an increased risk of complications.
Supports ablation feasibility in selected octogenarians without HF hospitalization; hypothesis-generating and requires randomized confirmation.
Catheter ablation is the first-line treatment for atrial fibrillation. Although the efficacy and safety of this procedure have been reported in older patients, they might diminish with age. Therefore, this study aimed to determine the safety and effectiveness of atrial fibrillation ablation in patients aged ≥80 years. We retrospectively analyzed the features of the catheter ablation and the subsequent clinical course and outcomes of 100 patients with atrial fibrillation aged ≥80 years who underwent ablation between July 2019 and December 2021 at Tosei General Hospital, Seto, Aichi, Japan. The average duration of atrial fibrillation was 6.0 ± 9.5 months, and 83% of the patients were symptomatic. Approximately 30% of patients developed heart failure, with 15% requiring hospitalization within one year before ablation. After ablation, 93% of patients were atrial fibrillation-free, and none required postoperative hospitalization due to heart failure. However, several complications have been observed, including cardiac tamponade, hematoma at the access site, and postoperative bradycardia. Notably, an enlarged left atrial diameter before ablation is a predictor of complications. In patients aged ≥80 years, atrial fibrillation ablation therapy demonstrated a high non-recurrence rate and may alter the progression of heart failure. Although the incidence of complications was relatively low, caution should be exercised when older patients with enlarged left atrial diameters undergo atrial fibrillation ablation.
No takes yet. Share an insight, caveat, or question.
Sakamoto et al. (2025) conducted an observational in atrial fibrillation (n=100). Catheter ablation was evaluated on Atrial fibrillation-free rate. Catheter ablation for atrial fibrillation in patients aged ≥80 years resulted in a 93% atrial fibrillation-free rate and zero postoperative hospitalizations for heart failure.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: