April 1, 2009Journal of Computers
The Analgoscore: A Novel Score to Monitor Intraoperative Nociception and its Use for Closed-Loop Application of Remifentanil
Why the study?
Does closed-loop administration of remifentanil using the Analgoscore improve intraoperative pain control compared to manual administration in patients undergoing general anesthesia?
Population
27 patients undergoing general anesthesia (16 in closed-loop group, 11 in control group)
Comparison
Closed-loop administration of remifentanil based… vs Manual administration of remifentanil by the…
Design
Cohort
Follow-up
intraoperative (approx 111 minutes)
Authors
Discussion
Loading...
Member takes
Implication
May support closed-loop remifentanil for modest pain control gains; leaves open need for randomized outcome trials.
Structured PICO
Does closed-loop administration of remifentanil using the Analgoscore improve intraoperative pain control compared to manual administration in patients undergoing general anesthesia?
P
Population
27 patients undergoing general anesthesia (16 in closed-loop group, 11 in control group)
I
Intervention
Closed-loop administration of remifentanil based on the Analgoscore (a score of intraoperative nociception based on mean arterial pressure and heart rate)
C
Comparator
Manual administration of remifentanil by the same anesthesiologist
O
Outcome
Percentage of anesthetic time within different control zones (excellent, good, insufficient pain control) and variability of mean arterial pressure and heart ratesurrogate
Closed-loop administration of remifentanil using the Analgoscore provides equal hemodynamic stability and pain control compared to meticulous manual administration during general anesthesia.
Cite This Study
Hemmerling et al. (2009) studied this question.