What question did this study set out to answer?

To evaluate and describe the response profiles of skin conductance and the analgesia-nociception index following standardized painful stimulation across varying remifentanil infusion rates in anesthetized pediatric patients.

November 21, 2012Pediatric Anesthesia

Pain monitoring in anesthetized children: first assessment of skin conductance and analgesia‐nociception index at different infusion rates of remifentanil

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Authors

NSNada SabourdinInserm MAMichel ArnaoutNational Institute for Health Research NLNicolas LouvetSorbonne Université

Discussion

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Implication

Prospective pilot study demonstrates superior sensitivity of the analgesia-nociception index over skin conductance in pediatric anesthesia, suggesting improved intraoperative pain tracking.

Key Points

To evaluate and describe the response profiles of skin conductance and the analgesia-nociception index following standardized painful stimulation across varying remifentanil infusion rates in anesthetized pediatric patients.
Enrolled 12 children (mean age 8.4 ± 5 years) undergoing middle-ear surgery maintained under desflurane anesthesia targeting a bispectral index of 50.
Administered remifentanil in 10-minute steady-state decrements (0.2, 0.16, 0.12, 0.08, and 0.04 μg·kg⁻¹·min⁻¹), delivering a standardized tetanic stimulation at the end of each period.
Measured heart rate, blood pressure, skin conductance, and analgesia-nociception index before and immediately after each painful stimulation.
Analgesia-nociception index dropped significantly following stimulation across all remifentanil doses compared with pre-stimulation baselines.
The post-stimulation drop in analgesia-nociception index was markedly larger at the lowest infusion rate of 0.04 μg·kg⁻¹·min⁻¹ compared to higher rates.
Skin conductance, heart rate, and blood pressure showed no significant alterations following electrical stimulation regardless of remifentanil dose.

Cite This Study

Sabourdin et al. (2012) studied this question.

synapsesocial.com/papers/6a7f6191fe225031baa72c4b https://doi.org/10.1111/pan.12071

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Implication

Prospective pilot study demonstrates superior sensitivity of the analgesia-nociception index over skin conductance in pediatric anesthesia, suggesting improved intraoperative pain tracking.

Pain monitoring in anesthetized children: first assessment of skin conductance and analgesia‐nociception index at different infusion rates of remifentanil

Discussion

Member takes

Implication

Key Points

Cite This Study

Pain monitoring in anesthetized children: first assessment of skin conductance and analgesia‐nociception index at different infusion rates of remifentanil

Discussion

Member takes

Implication

Key Points

Cite This Study

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