Key result
The correction of left bundle branch block by nonselective His bundle pacing may depend on functional lateral connections within the His bundle, challenging the concept of longitudinal dissociation.
The article discusses the theoretical mechanisms of QRS normalization during nonselective His bundle pacing, highlighting the potential role of functional lateral connections.
When those carrying out pacing of the His bundle found the procedure was able to correct the pattern of left bundle branch block, they presumed that the block was the consequence of discrete lesions in the His bundle. They further presumed that pacing distal to a discrete lesion produced normalization of the QRS complex.1,2 This novel concept was dependent on the assumption that the lesion was located in a longitudinally dissociated His bundle, ignoring evidence of functional lateral connections within the His bundle, which could theoretically circumvent an area of conduction block.
No takes yet. Share an insight, caveat, or question.
Mahmud et al. (2024) conducted an editorial in Left bundle branch block. Nonselective His bundle pacing was evaluated. The correction of left bundle branch block by nonselective His bundle pacing may depend on functional lateral connections within the His bundle, challenging the concept of longitudinal dissociation.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: