Key result
Surgical ventricular reconstruction improves symptoms and long-term survival for patients with ischemic cardiomyopathy and severe heart failure, achieving a 5-year survival rate of 51% in NYHA class IV patients.
Why the study?
Does surgical ventricular reconstruction improve clinical status and survival in patients with ischemic heart failure?
Does surgical ventricular reconstruction improve clinical status and survival in patients with ischemic heart failure?
Surgical ventricular reconstruction (the Dor procedure) is an effective non-transplant surgical option that reduces left ventricular volume, improves ejection fraction, and enhances survival in patients with ischemic dilated cardiomyopathy.
Supports surgical ventricular reconstruction in selected ischemic cardiomyopathy; leaves open need for randomized trials to confirm survival benefit.
Despite the improvements in the treatment of myocardial infarction that have translated into a decline in mortality rates, the incidence of heart failure has increased and, because of the limited number of cardiac donors, non-transplant heart surgery has developed in the past 10 years. Surgical ventricular reconstruction was launched by Dor and defined as endoventricular circular patch plasty repair. It represents a relatively novel surgical approach aiming to restore (bring back to normal) the dilated, distorted left ventricular (LV) cavity in order to improve function. The term ;surgical ventricular reconstruction/restoration' includes operative methods that reduce LV volume and restore its shape. The concept of reducing wall stress through surgical restoration of chamber size and geometry remains the guiding principle behind this innovative technique. Results from different Institutions are uniform and show an improvement in cardiac and clinical status and in survival. The present review will approach the rationale to re-shape the heart on the basis of pathophysiology and cardiac architecture, and will describe the efficacy of the Dor procedure in ischemic dilated cardiomyopathy, as well as some technical aspects and patient selection pathway.
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Donato et al. (2009) conducted a review in Ischemic heart failure. Surgical ventricular reconstruction (Dor procedure) was evaluated. Surgical ventricular reconstruction improves symptoms and long-term survival for patients with ischemic cardiomyopathy and severe heart failure, achieving a 5-year survival rate of 51% in NYHA class IV patients.
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