Key result
Moderate hemorrhage (average blood loss of 9.9% of estimated blood volume) in normal human blood donors caused no significant change in plasma antidiuretic hormone or plasma renin activity.
Why the study?
Does moderate hemorrhage alter plasma ADH and renin activity in normal human blood donors?
Population
24 normal human blood donors
Authors
Loading...
Should not yet change donor monitoring protocols; leaves open volume thresholds for ADH/renin activation.
Observational (n=24)
No
Does moderate hemorrhage alter plasma ADH and renin activity in normal human blood donors?
Moderate blood loss of approximately 10% of blood volume does not trigger significant changes in plasma ADH, renin activity, or vital signs in normal humans.
Goetz et al. (1974) conducted an observational in Normal human blood donors (n=24). Moderate hemorrhage was evaluated on Plasma antidiuretic hormone and plasma renin activity. Moderate hemorrhage (average blood loss of 9.9% of estimated blood volume) in normal human blood donors caused no significant change in plasma antidiuretic hormone or plasma renin activity.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: