Key result
Higher brachial-ankle pulse wave velocity at peritoneal dialysis initiation is linked to increased total mortality.
Why the study?
Does baseline brachial-ankle pulse wave velocity (baPWV) predict total mortality in incident peritoneal dialysis patients?
Cohort (n=254)
No
Does baseline brachial-ankle pulse wave velocity (baPWV) predict total mortality in incident peritoneal dialysis patients?
p-value: p=<0.001
Higher baseline brachial-ankle pulse wave velocity is an independent predictor of total mortality in incident peritoneal dialysis patients.
BACKGROUND AND OBJECTIVE: Elevated pulse wave velocity (PWV) has been associated with higher mortality in the general population, chronic kidney disease (CKD) patients, and hemodialysis patients. However, in peritoneal dialysis (PD) patients, this association has received little attention. The aim of this study was to evaluate the association between baseline brachial-ankle PWV (baPWV) levels and total mortality in PD patients. METHODS: In this single-center retrospective cohort study, 254 incident PD patients with baseline baPWV were followed up from 1 January 2013 to 31 July 2016. Collected baseline data included demographic characteristics and clinical and laboratory measurements. The association of baseline baPWV levels with total mortality was assessed using multivariable-adjusted Cox models. RESULTS: < 0.001). CONCLUSION: Higher baseline baPWV levels at the commencement of PD were independently associated with total mortality, which suggests that clinicians could use baPWV as a predictor of higher risk of mortality in PD patients.
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Wang et al. (2018) conducted a cohort in Peritoneal dialysis (n=254). Baseline brachial-ankle pulse wave velocity (baPWV) was evaluated on Total mortality (p=<0.001). Higher baseline brachial-ankle pulse wave velocity levels at the commencement of peritoneal dialysis were independently associated with total mortality (P<0.001).
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