Key result
Peripheral artery disease was a significant independent predictor of cardiovascular events in patients with HFpEF (HR 1.85; 95% CI 1.01-3.39; P=0.04).
Why the study?
Does brachial-ankle pulse-wave velocity and presence of peripheral artery disease predict cardiovascular outcomes in patients with HFpEF?
Population
502 patients with heart failure with preserved left ventricular ejection fraction (HFpEF)
Comparison
Measurement of brachial-ankle pulse-wave… vs Patients without PAD, and comparison across…
Design
Cohort
Follow-up
mean 1017 days
Authors
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May refine CV risk stratification in HFpEF; leaves open whether PAD-targeted interventions improve outcomes.
Cohort (n=502)
Does brachial-ankle pulse-wave velocity and presence of peripheral artery disease predict cardiovascular outcomes in patients with HFpEF?
Hazard Ratio: 1.85 (95% CI 1.01–3.39)
p-value: p=0.04
Identifying complications of PAD and measuring baPWV values in HFpEF patients can improve risk stratification for cardiovascular events.
Tokitsu et al. (2017) conducted a cohort in heart failure with preserved left ventricular ejection fraction (HFpEF) (n=502). Peripheral artery disease (PAD) vs. Without PAD was evaluated on cardiovascular events (HR 1.85, 95% CI 1.01-3.39, p=0.04). Peripheral artery disease was a significant independent predictor of cardiovascular events in patients with HFpEF (HR 1.85; 95% CI 1.01-3.39; P=0.04).
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