What question did this study set out to answer?

This research aims to examine the infection rates associated with ICD placements and the procedural factors influencing these rates.

August 1, 1998Clinical Infectious DiseasesOpen Access

Infections Associated with Implantable Cardioverter Defibrillators Placed Transvenously and via Thoracotomies: Epidemiology, Infection Control, and Management

Q: What is the clinical evidence from this study?

Study design: Observational. Population: Implantable cardioverter defibrillator (ICD) placement. Intervention: Single-stage procedure and transvenous ICD placement vs. Two-stage procedure and thoracotomy placement. Primary outcome: Incidence of infection associated with ICDs.

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Key result

The elimination of two-stage procedures and the shift to transvenous ICD placements decreased the infection rate from 16.7% to 0%.

Why the study?

Does single-stage transvenous ICD implantation reduce infection rates compared to two-stage thoracotomy procedures?

Key Points

This research aims to examine the infection rates associated with ICD placements and the procedural factors influencing these rates.
Analysis of infection rates from 1993 to 1995 during ICD placements at the institution.
Comparison of infection rates for transvenous and two-staged ICD placements.
Evaluation of procedural changes in the surgical approach to ICD implantations.
From 1992 to 1993, the infection rate dropped from 16.7% to 0%.
By 1995, the infection rate for implantable ICDs was 4.8%, aligning with literature ranges.
The transition to exclusively transvenous placement correlated with a significant reduction in infection rates.

Study Design

Type

Observational

Multicenter

Structured PICO

Does single-stage transvenous ICD implantation reduce infection rates compared to two-stage thoracotomy procedures?

Population

Patients undergoing implantable cardioverter defibrillator (ICD) placement at a single institution from 1992 to 1995

Intervention

Single-stage ICD implantation in the operating room and transvenous placement

Comparator

Two-staged ICD implantation (electrophysiologic study in lab, implantation in operating room later) and thoracotomy placement

Outcome

Incidence of infection associated with ICDssafety

Main Result

Absolute Event Rate: 0% vs 16.7%

The elimination of two-stage procedures and the shift to transvenous ICD placement significantly reduced device-associated infection rates.

Discussion

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Implication

May support single-stage transvenous ICDs to reduce infections; leaves open prospective validation in contemporary practice.

Cite This Study

Lai et al. (1998) conducted an observational in Implantable cardioverter defibrillator (ICD) placement. Single-stage procedure and transvenous ICD placement vs. Two-stage procedure and thoracotomy placement was evaluated on Incidence of infection associated with ICDs. The elimination of two-stage procedures and the shift to transvenous ICD placements decreased the infection rate from 16.7% to 0%.

synapsesocial.com/papers/6a07b5fb15d371b388386caa https://doi.org/10.1086/514673

Topics

Cardiac device therapy

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Infections Associated with Implantable Cardioverter Defibrillators Placed Transvenously and via Thoracotomies: Epidemiology, Infection Control, and Management

Key Points

Study Design

Structured PICO

Main Result

Discussion

Implication

Cite This Study

Topics

Infections Associated with Implantable Cardioverter Defibrillators Placed Transvenously and via Thoracotomies: Epidemiology, Infection Control, and Management

Key Points

Study Design

Structured PICO

Main Result

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider