Key result
Symptomatic postmenopausal women had a significantly higher LF/HF ratio compared to asymptomatic women (2.45 vs 1.18, P=0.027), indicating altered autonomic heart rate control.
Why the study?
Are postmenopausal symptoms associated with altered heart rate variability in middle-aged women?
Population
Middle-aged postmenopausal women
Comparison
Presence of postmenopausal symptoms vs Asymptomatic postmenopausal women
Design
Cross-sectional
Authors
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Menopausal symptoms were associated with higher LF/HF ratio; leaves open whether autonomic changes mediate cardiovascular risk.
Cross-Sectional (n=36)
No
Are postmenopausal symptoms associated with altered heart rate variability in middle-aged women?
Absolute Event Rate: 2.45% vs 1.18%
p-value: p=0.027
Postmenopausal symptoms, particularly hot flashes and sleep problems, are associated with increased sympathetic nerve activity as measured by heart rate variability.
Lee et al. (2011) conducted a cross-sectional in Menopausal symptoms (n=36). Symptomatic menopausal status (MRS ≥ 5) vs. Asymptomatic menopausal status (MRS < 5) was evaluated on LF/HF ratio (p=0.027). Symptomatic postmenopausal women had a significantly higher LF/HF ratio compared to asymptomatic women (2.45 vs 1.18, P=0.027), indicating altered autonomic heart rate control.
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