Key result
Higher LF/HF and S:PS HRV ratios link to worse glucose and lower HDL-C in young women.
Why the study?
The association of two different heart rate variability ratios with cardiovascular disease risk factors in young adults needed to be studied.
Are heart rate variability ratios associated with cardiometabolic risk factors in young adults?
Cross-Sectional (n=132)
Are heart rate variability ratios associated with cardiometabolic risk factors in young adults?
Heart rate variability ratios (LF/HF and S:PS) are associated with cardiometabolic risk factors, specifically glucose metabolism and HDL-C, in young women.
Answers are grounded in this paper and cite their sources.
Sex-specific HRV ratio associations with glucose markers and HDL-C in young women are hypothesis-generating; prospective studies needed before clinical use.
AIMS: To study the association of two different heart rate variability (HRV) ratios with cardiovascular disease (CVD) risk factors in young adults. METHOD: A total of 132 participants (89 women) were included in this cross-sectional study. We assessed their HRV and computed the low frequency-to-high frequency ratio (LF/HF) and, from the Poincaré plot, the ratio of the inverse of the longitudinal (SD2) to the transversal (SD1) axes ([1000/SD2]/SD1; sympathetic: parasympathetic [S:PS] ratio). From blood samples, we determined total cholesterol, high-density (HDL-C) and low-density lipoprotein-cholesterol, triglycerides, glucose, insulin, and the homeostatic model assessment of insulin resistance (HOMA) index. Multiple linear regression models were adjusted for age. RESULTS: Both, the LF/HF and the S:PS ratios, were positively associated with glucose metabolism markers (glucose, insulin, HOMA index), and negatively associated with HDL-C in women but not in men. CONCLUSION: We showed that the LF/HF and the S:PS are associated similarly with CVD risk factors in young women.
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Plaza‐Florido et al. (2022) conducted a cross-sectional in Cardiometabolic risk factors (n=132). Heart rate variability (HRV) ratios (LF/HF and S:PS) was evaluated on Association of HRV ratios with cardiovascular disease risk factors (lipids, glucose, insulin, HOMA index). Both the LF/HF and S:PS heart rate variability ratios were positively associated with glucose metabolism markers and negatively associated with HDL-C in young women, but not in men.
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