Why the study?
It is unknown whether decreased heart rate variability parallels or precedes manifest cardiovascular disease and how it relates to conventional risk factors in a healthy population.
Is there a relationship between decreased heart rate variability and conventional risk factors for cardiovascular disease in healthy 35-year-old subjects?
Comparison
Heart rate variability related to leucocyte count and blood lipoproteins by gender
Design
Cross-sectional spectral analysis of 24-hour ambulatory ECGs
Key result
In healthy 35-year-old adults, heart rate variability correlated with conventional cardiovascular risk factors, including a novel negative correlation with leucocyte count in men.
Authors
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HRV may signal early CV risk in healthy young adults; hypothesis-generating and should not yet alter practice or guidelines.
Cross-Sectional (n=133)
Yes
Is there a relationship between decreased heart rate variability and conventional risk factors for cardiovascular disease in healthy 35-year-old subjects?
Heart rate variability correlates with known cardiovascular risk factors, such as lipoproteins in women and leucocyte count in men, even in healthy 35-year-old individuals.
Jensen‐Urstad et al. (1998) conducted a cross-sectional in Healthy (n=133). Cardiovascular risk factors (including leucocyte count and blood lipoproteins) was evaluated on Correlation between spectral indices of heart rate variability and cardiovascular risk factors. In healthy 35-year-old adults, heart rate variability correlated with conventional cardiovascular risk factors, including a novel negative correlation with leucocyte count in men.
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