Key result
Conduction across the crista terminalis during 300 ms pacing showed significantly greater maximum split components in focal atrial fibrillation patients compared to controls (43 vs 16 ms, P<0.01).
Why the study?
What are the conduction characteristics at the crista terminalis during the onset of focal pulmonary vein atrial fibrillation compared to controls?
Observational (n=20)
What are the conduction characteristics at the crista terminalis during the onset of focal pulmonary vein atrial fibrillation compared to controls?
Absolute Event Rate: 43% vs 16%
p-value: p=<0.01
The study demonstrates anisotropic, decremental conduction across the crista terminalis during the onset of focal pulmonary vein atrial fibrillation, suggesting the development of a functional line of block.
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Greater crista terminalis splitting may facilitate focal AF maintenance; hypothesis-generating and requires prospective validation.
Fynn et al. (2004) conducted an observational in Focal atrial fibrillation (n=20). Analysis of conduction across the crista terminalis vs. Controls with no history of AF was evaluated on Maximum split components at the crista terminalis during pacing at 300 ms (p=<0.01). Conduction across the crista terminalis during 300 ms pacing showed significantly greater maximum split components in focal atrial fibrillation patients compared to controls (43 vs 16 ms, P<0.01).
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