Key result
Brachial artery flow-mediated dilatation in healthy children reached a peak of 7.7 +/- 4.0% at 79 +/- 33 seconds post-occlusion, requiring measurements up to 120 seconds to capture the true peak.
Why the study?
What is the optimal timing to measure peak brachial artery flow-mediated dilatation in healthy children?
Observational (n=105)
What is the optimal timing to measure peak brachial artery flow-mediated dilatation in healthy children?
p-value: p=<0.0001
Multiple brachial artery diameter measurements up to 120 seconds after cuff release are required to accurately capture the true peak FMD response in children.
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FMD protocols limited to 60 seconds may miss peak dilatation in children; leaves open need for revised timing standards in pediatric research.
Järvisalo et al. (2002) conducted an observational in Healthy (n=105). Forearm cuff occlusion-induced hyperemia was evaluated on Peak brachial artery flow-mediated dilatation (FMD) (p=<0.0001). Brachial artery flow-mediated dilatation in healthy children reached a peak of 7.7 +/- 4.0% at 79 +/- 33 seconds post-occlusion, requiring measurements up to 120 seconds to capture the true peak.
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