Key result
Early cardiac rehabilitation is linked to ~69% lower MACE versus no rehabilitation in post-MI HFrEF.
Why the study?
The study was conducted to evaluate the effectiveness of early cardiac rehabilitation on prognosis in patients who develop heart failure following acute myocardial infarction.
What are the key cardio-pulmonary exercise testing indicators that affect prognosis in patients undergoing early cardiac rehabilitation for heart failure following acute myocardial infarction?
Cohort (n=232)
No
What are the key cardio-pulmonary exercise testing indicators that affect prognosis in patients undergoing early cardiac rehabilitation for heart failure following acute myocardial infarction?
Absolute Event Rate: 18.2% vs 59.4%
p-value: p=0.005
In patients with heart failure post-myocardial infarction undergoing early cardiac rehabilitation, a specific parameter at anaerobic threshold (≤ 33.5 mmHg) serves as an independent risk factor for re-hospitalization.
May support early cardiac rehabilitation post-MI heart failure; leaves open confirmation by randomized trials and CPET threshold validation.
OBJECTIVE: The purpose of this retrospective study is to evaluate the effectiveness of early cardiac rehabilitation on patients with heart failure following acute myocardial infarction. METHODS: Two hundred and thirty-two patients who developed heart failure following acute myocardial infarction were enrolled in this study. Patients were divided into heart failure with reduced ejection fraction group (n = 54) and heart failure with mid-range ejection fraction group (n = 178). Seventy-eight patients who accepted a two-week cardiac rehabilitation were further divided into two subgroups based on major adverse cardiovascular events. Key cardio-pulmonary exercise testing indicators that may affect the prognosis were identified among the cardiac rehabilitation patients. RESULTS: at anaerobic threshold (≤ 33.5 mmHg) was an independent risk factor for re-hospitalization. CONCLUSIONS: at anaerobic threshold is an independent risk factor for re-hospitalization, and could be used as a evaluating hallmark for early cardiac rehabilitation.
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Cai et al. (2021) conducted a cohort in Heart failure following acute myocardial infarction (n=232). Early cardiac rehabilitation vs. Non-cardiac rehabilitation (generic instructions for maintaining physical activity) was evaluated on Major adverse cardiac events (MACE) in patients with HFrEF (p=0.005). Early cardiac rehabilitation significantly reduced major adverse cardiac events, including cardiogenic death and re-hospitalization, compared to non-rehabilitation in patients with heart failure following acute myocardial infarction.
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